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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459bf60686ac528931582197aabdf2b13f96f14dd66c5912fde231e694d9737b' 
  AND token = '0WzcZz2SlTEB3EG0TahJ4X4ZlJc653rfh4iV5Q+7H74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}