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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b9018fc9d0e8425b789030f9dce3c335ec9934015abbd5b7c11e76f6c4e748' 
  AND token = '1fFALa6wgmZw2z+WGczNRLsraqErNf4SBZNQpNbSW0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}