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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29009ef886a61cc65c352e241c6d31af5167d3228210ab0d6d1126e44c7dd586' 
  AND token = 'JT0w/6nhmgFpuW0qFFOgTHEKFkv+LWfMqNiDTFSW7Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}