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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b748eb8cdf4127e9539d3083a2d16efe97bca8b1933c71ee7ebcf64591eed54' 
  AND token = '3PVO+1L90yPMVamssSJ1Q3J4gTaGQNZFTeZcm8iQ/Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}