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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2409c1438aca90d394acc27da14d6bb255df7ead00e1861a8b5eb9a086e773f1' 
  AND token = '+rIoRvbuwzIE0oGXp6gqOG4hCnjtAt0kTdCUMUDeZH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}