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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780d8a89017eb839d032d4f36aee18ced3db7ad4429ac6640ac7753d56941744' 
  AND token = '6L/Vc5TLZt7jqm84eaGLzaSTVVklJ2AsrI/umKO4Wv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}