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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb724dd929a2cefaaed13ae8e40458080398eebce5f0ce5f939e859609b0f64b' 
  AND token = '2qtsM3piBbaMB1CsUe5B+GatyT7sejWvQDsyab7lsKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}