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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7890fb46f21c279b912c593e09689550d6fbd11d2c50b5c52632b90d9c902b22' 
  AND token = '9MGzLYpPMvQqmz72pN5F76BwHVetzhwrc67SuZgiFfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}