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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18df17c66ea7bb2f3d3b5b7b43d775b28f3a5be47ea826925712a8364696de8a' 
  AND token = '6XF1eiRG5eW2ma+EiyBko409CtaEFV2CaA7tFfkTjJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}