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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1818c78b4b08071d78b0d104cf36805af66c8922166c9e319b5723cd7f3bf0' 
  AND token = 'iS3638B8R8KtYIvUgG/NHec6ILZkb72OdrSt35LyQSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}