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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c828456c182be2efd6ac4c74492b0456ad7cb00b738f61ee60aead259acea8' 
  AND token = 'd/4FzB+rZWj9W9penzfUvOcmvmSxSLb6HRD+gbJ4+JI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}