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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b81d381ba9d528a0528ade332d079bf86c1a9813a2c162423235add87622015' 
  AND token = 'pTq+v58iYHU+0EnVLCbg8hDo2oh8vHlBKLkr/328evI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}