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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4919eb8ea57c1b3f9fbe1f571d07fe319c1312d50659a1d2ce8b9b77de83150c' 
  AND token = 'RTC1V4Qk2bfNxTIup3w89jHWQrO55VBgVu8AGbe3Y2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}