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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eeac3f0e109c8e2f4487b14bd997e61e4aca1c73d70527da75f91c4f5558687' 
  AND token = 'qMZaQ7kKRtEg3Qj+XkdBs/YMkYjg4J6Ei6muzxM5KR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}