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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd86c04d163f00542b9f82da4c88ea0b13509c96901aa01b29f3512ea8a1a2899' 
  AND token = 'p3YYb0uhU6k6igyHkK3rY6E0G5OPtvEgaSrd/u/8Zg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}