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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5e340ba157d36400d993d188a84a819f4c435ad2196a5a9c989691f294e927' 
  AND token = '3V+ooyhquPw3Ryli7klM//TLiKFWHwBL5L8WWrMEsuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}