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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c2a597c16abfbd707b3e78e1dc7989efb8b8c8f7267db2fae2e89d4fe12e42' 
  AND token = 'WXvdkBcscR/8M9qqF15o9Vi875rgxXxlqBX14R5A29I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}