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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d36457614854d52c486a212b98ebe2ead1507549e368f8d03b6b1916cd9289' 
  AND token = 'gS1OtVsNmGgxLcH8t7EZvLTr37LT2u3S4cHXFbxIXd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}