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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '952e4ffe19a262774fde7d390164bbb12d31312c37d72f4d10a897a18961a887' 
  AND token = 'RAJej3ww+xYQ1uUwnSRC0eyOVwk4vMTuI7vpwZeUWPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}