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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e085dc59a6d3c27e53659f14710a7144c5e9eb951068fd50b2be08bc56583c86' 
  AND token = 'ZmxhEujcg9xl7tp3cuxiCBZtBI/XBlRuaGV0WgxuQy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}