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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def139aa4276de2325843a6c91f3d0fe8d12460ce899a3f22b938df9faacea2e' 
  AND token = 'ePrZkCX11ebSgFMIfEIqQvSx3enirWZmRGbpAOIlnUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}