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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bb2ed4ed7c206099b5b41f8672fd0380ed3fea4399456982da888a102a7e38' 
  AND token = 'ssCs1m2gaCHr2nPXHA65VJjjUc3vD6tW/PwRUhiJatE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}