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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8449ab43330a8c80aeee2ae8ab6555cf4e4d9411d248118237c5a8f0e02add68' 
  AND token = 'm72IG13MdkSEhbtY53d0OwpWoqqmX33N0KYNe4GQTfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}