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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eea9c8b6cb459522c5345902c21bfa08e9305374db0b7b0cc3afeda27ba100d' 
  AND token = 'ex9/DbDJiXPGh2gj/EdpFMwaBDXL+c1jgX8Rpawy2rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}