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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0010a3f801eab4d33dfcbc900acef7ad1f88ac37246ca423f55925ed5356cff' 
  AND token = 'zg6Mybb8bCt6N+OiJzEHICXTeWfVlnzDqjY5CPTP8sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}