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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d2ac8a4df4b18c7bd8ba629c6b1661c3113ddd8da14c518f303c39e78dc12a' 
  AND token = 'XZxxMMYmkMgNaxjacy56Xuweh3XFGtw5BeGEje6bLTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}