SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c8ef3c14a8d51eee23edb76552053912ad13ae219ae80b4492b9ea01d00fca' 
  AND token = '0IiWmmJ6tpTfrRDWaJJ6H4l2r+fpLdu3lmKcctN1Nhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}