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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb2205a23d8e07cec6a7c6f88f0790c85b6e80aa363bb22cb4db1c4210cf53c' 
  AND token = 'S+YCDhuqq8OckUVFzykcqa5M2UDsB/tXw+BRQrpsAmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}