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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd544849ef216c9853062f25554f702df00c7e21d4593ffcf3f9d9c289b16a5b8' 
  AND token = 'ttpFHM3/H3y5A3dOxChQMFEoQIHj49U8/vMukFhOYWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}