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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a481c2c7b1ee1502a4d69c6e507a1c92b195f1c4e0491773713708508316480' 
  AND token = 'Kk4pXB9aTZZWFgRhTSSTvkpRwLjTDg40xbseqRiWSAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}