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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '853569e2e4567cf3c4e8bd83fec7638dfa12a759f8a4385824c755981fcef357' 
  AND token = 'MJwIOXFz9Z81+RPJQY5t8uTm9bAv4CJAbUV3puT7J1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}