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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8782e35ba0fab53fd10a7b48f532f82c1f878c2236f01d180ef8e96113755a56' 
  AND token = 'V4y1WD4Bw95CPwT0n15HC0Xg/hKKj19R0HlKdmvuxQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}