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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ae0c89f31a72509cb23aa5b87ba7f5dd098eb343d1219e26c3edab64ac1cf4' 
  AND token = 'Y5NJOFh4xSOZY+1uvK3d3uNbSmrrr17kNOnDZACHWPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}