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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42723a91463bea9db01f829166f3b7a7d514ad4021bd59ec41c468f233adafca' 
  AND token = 'Lsy0lp4z+ZeYIk3IfHUAZPMYO/+U9W1DqShq10VbZOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}