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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef76a8522c8f03321dfcfc61a28bcb0f0f7e2b1ee50b8c0fabf09a99bd36f5c2' 
  AND token = '4NOXbBvBRch9EB/Mxpk6T8QOuUviZETjBm/LN2Nd23g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}