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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e32682ef1629e7921f77c0818257aa83002b06b3dde713dcb4cb9a1b1df221' 
  AND token = 'mB9eW/6ODPAeZ37cwgHtj7XKaf2t0eqTM7rWEl7ccHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}