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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3421b2582dd2089b1e779363a325eb7399e42b93a11cbc2ff18a50186da3bd2' 
  AND token = '+3vS5pABN2jV1jK5MKwEfJIuyX0cZOTBBPAJTOFjQUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}