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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da21564fd1f064a062b0780e8ee82e5f98d033a3096cbde08b6dbec89bd8ba07' 
  AND token = '8e/V7dJZQso4ztshorzKflv9qkrBj3K5kZ/osqUXNFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}