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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22eeb910de2039a708b17bd2f1efa0d9666ebdaa47b56875b1ff5ea65182b6f' 
  AND token = 'cF+H5MbQRPkcesc6LnIdkmFjogjWYD94IUvwtz1YjU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}