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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe42879c25b3ea1c1e3f6bf908abe0d06a9e6bb15b0b2c82d177476752ce0739' 
  AND token = 'PAE3I+1DpQLnx8pD7/+6OK+0qX+wj6Ry5cEG+l2tZkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}