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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3fc21e751f5df8a1e2c4446bac9f4158268be8599518ad65faa709b1d96a214' 
  AND token = 'rGHPLlfpVa/fK81+CCKLSOrw8hrdlS5tj+S1erYRrgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}