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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c25d4d8944ecc3c0fd64c3768083de762ec3b7f2cdec6a79964c5df51db53c4' 
  AND token = 'iordV7AM3CtAl0CUoettrOSeW1QTqseb9GPd7OiVRfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}