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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c176aca945b6b2867cc33e8cffc21f52ee4fef01be22d0a1809c3e3c9c31a05' 
  AND token = '6birmlKVL2B02+xuLlnmM2SNLDRRlee03YHFGlAHP5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}