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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866532a5bdd717754a9f9d2a6a32a2c8bfcca43e6196fc437e48c3a2681b454c' 
  AND token = 'lx1MMugpLM6xwKqa/WljQSA3Lcp7c6VeR0J9oKUxzQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}