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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721700be8ba72d314d9a70e2232fba5d6bd2a95d24ab2a276118b9deac7f9d9b' 
  AND token = '1GBRCvsXz0tBrMea+gwIWExSyq7uISZv0NL6ELv4l3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}