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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9851e38148e6329b9561df13a1002a94976a5d3612de3b509a07224513c3584' 
  AND token = 'PKqa/On8w528Zp+7R5w/UNj8hWbymp0UoVpkHf0YYWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}