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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5034b46f3a1451c3a8924e0bea547601e3bc78a50db82212cbbb9e73f6fd757e' 
  AND token = 'HkcWg2WgVkXvDgKH+JzeHwW0dPSXiPdzgUbfpr5V/1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}