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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f13a99a4b787549895f19e3ab95c960b05d6a02502edb9c21b28c11f9f2a5c' 
  AND token = 'cXok2DenEDaTS1reyDM0qieSi6dL08qmJj/X9SAFQpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}