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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '302083a497890db28b9a99c67a2d1da8c4e0bb7fc5512c5f1675d17de21f441c' 
  AND token = 'mCbgC8OMqEHjYEp1x77excPgT9T69TKPuxxfKLnKzdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}