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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e923e6caa87bff4b9b1163191c00c042fe50cfb1c96316e3649f6d9533f6360' 
  AND token = 'Ih/e9ba+F1S6FAk9ALPjwHR4FcWEjz2KckLnjcaIVKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}